Aquaretic

An agent that bind to vasopressin receptors in the renal collecting duct, promoting excretion of solute-free water [Saunders2007].

There appear to be different modes of action. In general, synthetic aquaretic agents antagonize the vasopressin V2 receptor in the kidney, preventing reabsorption of water [https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/aquaretic].

On the other hand, herbal aquaretics act by increasing glomerular filtration rate [https://www.chicagotribune.com/news/ct-xpm-1999-05-21-9905220023-story.html], [https://www.gruenwalder.de/english/products/asparagus-p/aquaresis.html].

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  Renal System

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[Saunders2007] Saunders Comprehensive Veterinary Dictionary, 3 ed. © 2007 Elsevier. Retrieved June 4 2016 from http://medical-dictionary.thefreedictionary.com/aquaretic.